Endocrine Abstracts

Introduction: Oxidative stress has been implicated in the pathogenesis of many thyroid diseases, such as non-toxic nodular goiter and Hashimoto’s thyroiditis. Nitric oxide synthases are responsible for the synthesis of nitric oxide from L-arginine. There are three isoforms of nitric oxide synthase (NOS): neuronal NOS (nNOS), endothelial NOS (eNOS) and inducible NOS (iNOS). They have important functions in inflammation and vasoregulation but their role in thyroid diseases ...

Introduction: Thyroid goiter may be present in different thyroid pathologies, such as non-toxic nodular goiter (NTNG) or Hashimoto’s thyroiditis (HT), as a result of focal hyperplasia of thyrocytes (nodal goiter) or generalized enlargement of thyroid (diffuse goiter). Previous studies have demonstrated that programmed cell death, known as apoptosis, plays an important role in the pathogenesis of many thyroid diseases, especially inflammatory conditions.<p class="abste...